Calcium and epithelial cell proliferation.

  title={Calcium and epithelial cell proliferation.},
  author={Alton L. Boynton},
  journal={Mineral and electrolyte metabolism},
  volume={14 1},
The extracellular calcium ion is required for the proliferative activity of a wide variety of nonneoplastic epithelial cells both in vivo and in vitro. This dependence in vitro appears to be density-dependent with sparse cultures unable to proliferate in Ca2+-deficient medium while dense culture can proliferate despite the Ca2+ deficiency. Some epithelial… CONTINUE READING