Calcium and angiotensin tachyphylaxis in rat uterine smooth muscle.

  • R J Freer
  • Published 1975 in The American journal of physiology


Studies were carried out to investigate the relationship between extracellular Ca++ and the ability of a particular smooth muscle to develop tachyphylaxis to angiotensin II (AII). Stimulation of rat uterus by AII was found to be dependent on extracellular Ca++. Placing the tissue in 0 Ca++ completely blocked AII-induced contractions as did the presence of… (More)