Calcium and Weight: Clinical Studies

  title={Calcium and Weight: Clinical Studies},
  author={Robert Proulx Heaney and K. Michael Davies and M. Janet Barger-Lux},
  journal={Journal of the American College of Nutrition},
  pages={152S - 155S}
Key MethodData from six observational studies and three controlled trials in which calcium intake was the independent variable (and either bone mass or blood pressure the original outcome variable) have been reanalyzed to evaluate the effect of calcium intake on body weight and body fat. Analysis reveals a consistent effect of higher calcium intakes, expressed as lower body fat and/or body weight, and reduced weight gain at midlife. Similarly, studies relating nutrient intake to body composition report…
Calcium supplementation for 1 y does not reduce body weight or fat mass in young girls.
Habitual dietary calcium intake was inversely associated with body fat, but a low-dose calcium supplement had no effect on body weight, height, or body fat over 1 y in young girls.
Relationship Between Calcium Intake and Anthropometric Indices
Available data do not unequivocally support the hypothesis that a causal relationship exists between high dairy food intake and/or high dietary calcium intake and lower fat mass deposition, and daily calcium intake should, however, be encouraged to achieve optimal health.
Calcium intake and the outcome of short-term weight management.
There was no significant difference in weight loss in response to WM between the placebo-treated and calcium-treated groups, however, addition of calcium to the diet resulted in a lower hunger score in the Eating Inventory as well as a decrease in plasma resistin levels.
Association of Calcium Intake and Adiposity in Postmenopausal Women
Increased calcium intake was associated with lower percent body fat and higher dairy intake wasassociated with lower fat mass in postmenopausal women, but there was no association between calcium intake and body fat distribution measures in this population.
Habitual dietary calcium intake and body weight in 7–10 year old children
Investigation of possible associations between habitual calcium intake and body weight in a group of 7–10 years old children suggested that girls have significantly lower intakes of calcium than boys.
The influence of calcium supplement on body composition, weight loss and insulin resistance in obese adults receiving low calorie diet
Results from this study suggest that 24 weeks of supplementation with 1000 mg ca/d did not have any effect on weight, body composition, insulin resistance and blood pressure beyond what can be achieved in an energy restricted diet in obese adults.
Normalizing calcium intake: projected population effects for body weight.
  • R. Heaney
  • Medicine, Geology
    The Journal of nutrition
  • 2003
Although calcium intake explains only a small fraction of the variability in weight or weight gain, shifting the mean of the distributions downward by increasing calcium intake can be estimated to reduce the prevalence of overweight and obesity by perhaps as much as 60-80%.
Dietary calcium intake of 1200 mg-d may have negative correlation on percent body fat: A cross-sectional study
There may be association between daily ingestion of at least 1200 mg of calcium and decreased percent body fat in premenopausal Caucasian women.
Effects of dietary calcium intake on body weight and prevalence of osteoporosis in early postmenopausal women.
In early postmenopausal women, a low dietary calcium intake may increase the risk of osteoporosis, but its negative effect can be offset by the greater BMI found in women with a low calcium intake.
Effect of calcium intake on fat oxidation in adults: a meta‐analysis of randomized, controlled trials
The effects of acute high calcium intake appear to point in the same direction, but further work is needed to permit a greater degree of certainty on how this effect is likely to increase rates of fat oxidation.


Calcium intake and body weight.
Estimates indicate that a 1000-mg calcium intake difference is associated with an 8-kg difference in mean body weight and that calcium intake explains approximately 3% of the variance in body weight.
Dairy Calcium is Related to Changes in Body Composition during a Two-Year Exercise Intervention in Young Women
Cal calcium adjusted for energy intake had a negative relationship and vitamin A intake a positive relationship with two year changes in total body weight and body fat in young women aged 18 to 31 years in this randomized exercise intervention trial.
The role of dietary calcium and other nutrients in moderating body fat in preschool children
Higher longitudinal intakes of calcium, monounsaturated fat, and servings of dairy products were associated with lower body fat.
Ethnic differences in dietary intakes, physical activity, and energy expenditure in middle-aged, premenopausal women: the Healthy Transitions Study.
Ethnic differences in EE and the intake of certain nutrients may influence the effect of menopausal transition on obesity in African American women.
Dietary calcium induces regression of left ventricular hypertrophy in hypertensive non-insulin-dependent diabetic blacks.
The data indicate that calcium supplementation sufficient to normalize dietary calcium in black hypertensive diabetic men significantly reduces vascular resistance and causes partial regression of LVH.
Regulation of adiposity by dietary calcium
Increasing dietary calcium suppresses adipocyte in‐tracellular Ca2+ and thereby modulates energy metabolism and attenuates obesity risk, and this concept of calcium modulation of adiposity was further evaluated epi‐demiologically in the NHANES III data set.
Randomised controlled trial of novel, simple, and well supervised weight reducing diets in outpatients
Dietary treatment can achieve as much weight loss in obese outpatients over 16 weeks as has been reported for the most successful drug treatment, but compliance with the prescribed diet is poor unless the diet is novel and simple.
Inpatient-outpatient randomized comparison of Cambridge diet versus milk diet in 17 obese women over 24 weeks.
Twenty-two obese women were recruited for a prospective cross-over trial of the effects of either the Cambridge Diet (CD) or 1200 ml milk with iron and vitamin supplements (milk) during a three-week
Parathyroid ablation in dystrophic hamsters. Effects on Ca content and histology of heart, diaphragm, and rectus femoris.
The data suggests that in chronically TPTX hamsters fed a standard laboratory diet, plasma Ca can be maintained by mechanisms independent of parathyroid function, and chronic TPTx in dystrophic hamsters reduces, but does not arrest, the Dystrophic process.
Calcium paradox disease: Calcium deficiency prompting secondary hyperparathyroidism and cellular calcium overload
In this review, evidence supporting the concept of calcium paradox disease is presented from the viewpoints of epidemiology, clinical evidence, experimental models, and cell biology.