Calcium and Neuromuscular Transmission

  title={Calcium and Neuromuscular Transmission},
  author={W. Kloot},
  • W. Kloot
  • Published 1978
  • Chemistry
  • The importance of Ca2+ in the release of ACh at the neuromuscular junction was shown by experiments of such lucid design and clever execution that they became instant classics (summarized by Katz, 1969). The general opinion is that depolarization of the nerve terminal opens a voltage-gated Ca2+ channel, Ca2+ enters the terminal to initiate quantal release which ends when the Ca2+ is sequestered or ejected from the terminal. This clear picture, naturally enough, hides uncertainties and… CONTINUE READING
    21 Citations
    The pharmacological effects of cadmium on skeletal neuromuscular transmission.
    • 11
    Stimulation of the frequency of MEPPs at the frog neuromuscular junction by extracellular EGTA
    • 3


    Action of Co and Ni at the frog neuromuscular junction.
    • 49
    Antagonism between Na+ and Ca2+ at the Neuromuscular Junction
    • 59
    Co‐operative action of calcium ions in transmitter release at the neuromuscular junction
    • 1,155
    Strontium and quantal release of transmitter at the neuromuscular junction
    • 174
    The effect of calcium on acetylcholine release from motor nerve terminals
    • B. Katz, R. Miledi
    • Chemistry, Medicine
    • Proceedings of the Royal Society of London. Series B. Biological Sciences
    • 1965
    • 603
    An analysis of the role of calcium in facilitation at the frog neuromuscular junction
    • S. Younkin
    • Chemistry, Medicine
    • The Journal of physiology
    • 1974
    • 71