Calcium and Membrane Potential Oscillations in Pancreatic-Cells

  title={Calcium and Membrane Potential Oscillations in Pancreatic-Cells},
  author={Arthur Sherman},
We study pancreatic -cells because of their role in diabetes, a deadly derangement of carbohydrate and lipid metabolism. Their function is to secrete insulin in response to elevations of glucose in the blood plasma, as after a meal. Insulin signals the target tissues (muscle, liver, and adipose cells) that glucose is available for use as a fuel or for storage as glycogen or fat. Later, as plasma glucose declines, insulin secretion returns to basal levels, and cells switch back to using stored… CONTINUE READING
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