Calcium absorption on high and low calcium intakes in relation to vitamin D receptor genotype.


The finding that the link between polymorphism at the vitamin D receptor (VDR) gene and rates of bone loss from the femoral neck in postmenopausal women is enhanced at low calcium intakes suggests that intestinal calcium absorption is a site of differential action of the VDR alleles. 1,25-Dihydroxyvitamin D [1,25-(OH)2D] and its receptor mediate active… (More)


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