Calcium Supplements for the Prevention of Colorectal Adenomas

  title={Calcium Supplements for the Prevention of Colorectal Adenomas},
  author={Beldhuis Hans J.A. and {\'A}ron and M J.S. and ANDEL and R. UdoSchlaudraffPastori. and M M Van and Tolk and S. SaiSiddhardhaR. and ANDLER and R. Ruby and OTHSTEIN and S R.W. and UMMERS and Stephen F. Shafizadeh D.C. and Nover and G E.R. and REENBERG},
A BSTRACT Background and Methods Laboratory, clinical, and epidemiologic evidence suggests that calcium may help prevent colorectal adenomas. We conducted a randomized, double-blind trial of the effect of supplementation with calcium carbonate on the recurrence of colorectal adenomas. We randomly assigned 930 subjects (mean age, 61 years; 72 percent men) with a recent history of colorectal adenomas to receive either calcium carbonate (3 g [1200 mg of elemental calcium] daily) or placebo, with… CONTINUE READING
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