Calcium-Sensing Receptor Genotype and Response to Cinacalcet in Patients Undergoing Hemodialysis.

@article{Moe2017CalciumSensingRG,
  title={Calcium-Sensing Receptor Genotype and Response to Cinacalcet in Patients Undergoing Hemodialysis.},
  author={Sharon M. Moe and Leah Wetherill and Brian Scott Decker and Dongbing Lai and Safa Abdalla and Jin Long and Matteo Vatta and Tatiana Foroud and Glenn M. Chertow},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  year={2017},
  volume={12 7},
  pages={
          1128-1138
        }
}
BACKGROUND AND OBJECTIVES We tested the hypothesis that single nucleotide polymorphisms (SNPs) in the calcium-sensing receptor (CASR) alter the response to the calcimimetic cinacalcet. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS We analyzed DNA samples in the Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) trial, a… CONTINUE READING