Calcium Chelation by Alginate Activates the Type III Secretion System in Mucoid Pseudomonas aeruginosa Biofilms

Abstract

The extracellular biofilm matrix includes primarily DNA and exopolysaccharides (EPS), which function to maintain aggregate structures and to protect biofilms from antibiotics and the immune response. Both polymers are anionic and have cation binding activity, however the impact of this activity on biofilms is not fully understood. Host cell contact is… (More)
DOI: 10.1371/journal.pone.0046826

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Cite this paper

@inproceedings{Horsman2012CalciumCB, title={Calcium Chelation by Alginate Activates the Type III Secretion System in Mucoid Pseudomonas aeruginosa Biofilms}, author={Shawn R. Horsman and Richard A. Moore and Shawn Lewenza}, booktitle={PloS one}, year={2012} }