Calcium‐calmodulin signalling pathway up‐regulates glutamatergic synaptic function in non‐pyramidal, fast spiking rat hippocampal CA1 neurons

@article{Wang2001CalciumcalmodulinSP,
  title={Calcium‐calmodulin signalling pathway up‐regulates glutamatergic synaptic function in non‐pyramidal, fast spiking rat hippocampal CA1 neurons},
  author={Jin‐Hui Wang and Paul Kelly},
  journal={The Journal of Physiology},
  year={2001},
  volume={533}
}
  • Jin‐Hui Wang, Paul Kelly
  • Published 2001
  • Biology, Medicine
  • The Journal of Physiology
The role of Ca2+‐calmodulin (CaM) signalling cascades in modulating glutamatergic synaptic transmission on CA1 non‐pyramidal fast‐spiking neurons was investigated using whole‐cell recording and perfusion in rat hippocampal slices. Paired stimuli (PS), consisting of postsynaptic depolarization to 0 mV and presynaptic stimulation at 1 Hz for 30 s, enhanced excitatory postsynaptic currents (EPSCs) on non‐pyramidal neurons in the stratum pyramidale (SP). The potentiation was reduced by the… Expand
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