Calcium: a potential central regulator in wound healing in the skin

@article{Lansdown2002CalciumAP,
  title={Calcium: a potential central regulator in wound healing in the skin},
  author={Alan B. G. Lansdown},
  journal={Wound Repair and Regeneration},
  year={2002},
  volume={10}
}
  • A. Lansdown
  • Published 1 September 2002
  • Biology, Medicine
  • Wound Repair and Regeneration
Calcium has an established role in the normal homeostasis of mammalian skin and serves as a modulator in keratinocyte proliferation and differentiation. Gradients of calcium concentration increasing from 0.5 mM in the basal layer to > 1.4 mM in the stratum granulosum are consistent with migration patterns in response to minor abrasion (normal wear). Dermal fibroblasts require calcium but are approximately 100 times less sensitive than keratinocytes. Normal calcium metabolism in the skin is… 
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