Calcium, calmodulin and cell proliferation.

@article{Means1988CalciumCA,
  title={Calcium, calmodulin and cell proliferation.},
  author={Anthony R. Means and Colin Dale Rasmussen},
  journal={Cell calcium},
  year={1988},
  volume={9 5-6},
  pages={
          313-9
        }
}
Calcium and calmodulin have been proposed to be regulatory factors in cell cycle progression. Clonal mouse cell lines harboring episomally-carried genes have been prepared to address this question. Some lines produce extra calmodulin, others express antisense RNA to decrease calmodulin, while others produce the Ca2+-buffering protein parvalbumin. The results show that calmodulin acts at two points in the cell cycle--the G1/S boundary and metaphase transition. An additional Ca2+ event that is… CONTINUE READING
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