Calcitriol started in the donor, expands the population of CD4+CD25+ T cells in renal transplant recipients.

@article{Ardalan2007CalcitriolSI,
  title={Calcitriol started in the donor, expands the population of CD4+CD25+ T cells in renal transplant recipients.},
  author={Mohammed Reza Ardalan and H Maljaei and Mohammadali M Shoja and Ali Piri and Hamid Tayebi Khosroshahi and Hamid Noshad and Hassan Argani},
  journal={Transplantation proceedings},
  year={2007},
  volume={39 4},
  pages={951-3}
}
OBJECTIVES Alloreactive T cells recognize antigens via direct and indirect pathways. The competency of costimulatory molecules on antigen-presenting cells (APC) is important. An active form of vitamin D (1,25(OH)(2)D(3), calcitriol) inhibits APC cell maturation and expression of costimulatory molecules. Herein we studied the immunosuppressive effects of calcitriol, which was started in the donors and continued in the kidney recipients. METHODS In this prospective study, candidates for living… CONTINUE READING

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The control group received the conventional immunosuppressive regimen , namely , cyclosporine / mycophenolate mofetil and prednisolone .
The control group received the conventional immunosuppressive regimen , namely , cyclosporine / mycophenolate mofetil and prednisolone .
The control group received the conventional immunosuppressive regimen , namely , cyclosporine / mycophenolate mofetil and prednisolone .
The control group received the conventional immunosuppressive regimen , namely , cyclosporine / mycophenolate mofetil and prednisolone .
The control group received the conventional immunosuppressive regimen , namely , cyclosporine / mycophenolate mofetil and prednisolone .
The control group received the conventional immunosuppressive regimen , namely , cyclosporine / mycophenolate mofetil and prednisolone .
The control group received the conventional immunosuppressive regimen , namely , cyclosporine / mycophenolate mofetil and prednisolone .
An active form of vitamin D ( 1,25(OH)(2)D(3 ) , calcitriol ) inhibits APC cell maturation and expression of costimulatory molecules .
The control group received the conventional immunosuppressive regimen , namely , cyclosporine / mycophenolate mofetil and prednisolone .
The control group received the conventional immunosuppressive regimen , namely , cyclosporine / mycophenolate mofetil and prednisolone .
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