Calcitriol for bone loss in patients with primary biliary cirrhosis

  title={Calcitriol for bone loss in patients with primary biliary cirrhosis},
  author={Susumu Shiomi and Kyoko Masaki and Daiki Habu and Tadashi Takeda and Shuhei Nishiguchi and Tetsuo Kuroki and Hironobu Ochi},
  journal={Journal of Gastroenterology},
Because osteoporosis is a common complication of primary biliary cirrhosis, we evaluated the effects of calcitriol (1α, 25-dihydroxyvitamin D3) on bone mineral density in 34 women with primary biliary cirrhosis (stage I disease in 16 patients, stage II in 9, stage III in 4, and stage IV in 5). Patients were assigned randomly to receive calcitriol (0.5 mg twice a day) or not. Bone mineral density of the lumbar vertebrae was measured by dual-energy X-ray absorptiometry at least twice during a… CONTINUE READING


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