Calcitonin measurement to detect medullary thyroid carcinoma in nodular goiter: German evidence-based consensus recommendation.

@article{Karges2004CalcitoninMT,
  title={Calcitonin measurement to detect medullary thyroid carcinoma in nodular goiter: German evidence-based consensus recommendation.},
  author={Wolfram Karges and Henning 5 Dralle and F Raue and Klaus Mann and Christopher Reiners and M. Gru\ssendorf and Michael H{\"u}fner and Bruno Niederle and Georg Brabant},
  journal={Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association},
  year={2004},
  volume={112 1},
  pages={52-8}
}
Serum calcitonin (CT) has become a very specific and sensitive marker for human medullary thyroid carcinoma (MTC), a neuroendocrine tumor affecting about 1 % of patients with nodular thyroid disease. MTC is characterized by early micrometastasis and a lack of curative non-surgical treatment, so that early diagnosis is desirable. Based on a systematic review of scientific evidence, we propose multidisciplinary consensus recommendations for the clinical use of CT in patients with nodular goiter… CONTINUE READING

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