• DOI:10.1038/313054A0
Corpus ID: 4329128

Calcitonin gene-related peptide is a potent vasodilator

@article{Brain1985CalcitoninGP,
  title={Calcitonin gene-related peptide is a potent vasodilator},
  author={S. Brain and T. Williams and J. R. Tippins and H. Morris and I. Macintyre},
  journal={Nature},
  year={1985},
  volume={313},
  pages={54-56}
}

S. Brain, T. Williams, +2 authors I. Macintyre

Published 1985

Chemistry, Medicine

Nature

A novel peptide, calcitonin gene-related peptide (CGRP), has been predicted to result from alternative processing of the primary RNA transcript of the calcitonin gene in the rat1,2. Several lines of evidence suggest that CGRP is a transmitter in the central and peripheral nervous system2–4. Human CGRP has been isolated and characterized5, and shown to have potent effects on the heart6. The observations presented here indicate that human and rat CGRP also have potent effects on blood vessels… CONTINUE READING

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