Calcitonin gene-related peptide: potent vasodilator and major product of calcitonin gene.

@article{Girgis1985CalcitoninGP,
  title={Calcitonin gene-related peptide: potent vasodilator and major product of calcitonin gene.},
  author={Samia I. Girgis and Donald Macdonald and J. Court Stevenson and Peter J. R. Bevis and Catherine Lynch and Sunil J. Wimalawansa and Colin H. Self and Howard R. Morris and Iain Macintyre},
  journal={Lancet},
  year={1985},
  volume={2 8445},
  pages={14-6}
}
In addition to calcitonin and katacalcin, the human calcitonin gene encodes a novel peptide--calcitonin gene-related peptide (CGRP)--a potent vasodilator. A sensitive and specific radioimmunoassay was developed to study plasma levels of CGRP in normal subjects. CGRP circulates at five times the concentration of calcitonin, suggesting that it may be an… CONTINUE READING