Calcitonin and calcitonin gene-related peptide interact with the same receptor in cultured LLC-PK1 kidney cells.

@article{Wohlwend1985CalcitoninAC,
  title={Calcitonin and calcitonin gene-related peptide interact with the same receptor in cultured LLC-PK1 kidney cells.},
  author={Annelise Wohlwend and Kerstin Malmstr{\"o}m and Heino Henke and Heini Murer and Jean Dominique Vassalli and Jan A. Fischer},
  journal={Biochemical and biophysical research communications},
  year={1985},
  volume={131 2},
  pages={537-42}
}
Calcitonin and calcitonin gene-related peptide stimulate adenylate cyclase activity and plasminogen activator production in cultured renal tubular LLC-PK1 cells. Salmon [125I]calcitonin and human [125I]calcitonin gene-related peptide bound specifically to the cells. Salmon [125I]calcitonin binding was reduced at lower concentrations of non-radioactive salmon calcitonin than of human calcitonin gene-related peptide. For the stimulation of adenylate cyclase activity and plasminogen activator… CONTINUE READING