Calcitonin Gene‐Related Peptide in the Regulation of Cardiac Function a

  title={Calcitonin Gene‐Related Peptide in the Regulation of Cardiac Function a},
  author={Katsutoshi Goto and Takashi Miyauchi and Satoshi Homma and Norio Ohshima},
  journal={Annals of the New York Academy of Sciences},
Traditionally, autonomic cardiovasclar control has been attributed solely to adrenergic (sympathetic) and cholinergic (parasympathetic) neurotransmitters. It has recently been revealed that the cardiac and vascular tissues are also innervated by peptidergic neurons that may mediate nonadrenergic noncholinergic (NANC) functions. Among the neuropeptides, calcitonin gene-related peptide (CGRP) is of particular interest for the following reasons. First, it is expressed in a quite unusual way: an… 

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In addition to calcitonin and katacalcin, it is now known that the human calcitonin gene encodes a novel peptide called calcitonin gene related peptide (CGRP). In experimental animals, CGRP produces

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