Calcineurin inhibitor-free immunosuppression in pediatric renal transplantation: a viable option?


The introduction, in the mid-1980s, of calcineurin inhibitors - namely ciclosporin (cyclosporine) and later tacrolimus - has significantly improved short-term renal graft survival by lowering acute rejection rates in both adult and pediatric kidney transplantation. Nonetheless, long-term transplant survival is still not satisfactory, with calcineurin… (More)
DOI: 10.2165/11538530-000000000-00000


5 Figures and Tables