Calcineurin inhibitor-free graft-versus-host disease prophylaxis with sirolimus and mycophenolate mofetil in a second allogeneic stem cell transplantation for engraftment failure and rituximab-refractory Epstein-Barr virus-induced posttransplant lymphoproliferative disease.

@article{Ceppi2014CalcineurinIG,
  title={Calcineurin inhibitor-free graft-versus-host disease prophylaxis with sirolimus and mycophenolate mofetil in a second allogeneic stem cell transplantation for engraftment failure and rituximab-refractory Epstein-Barr virus-induced posttransplant lymphoproliferative disease.},
  author={Francesco Ceppi and Michel Duval and Pierre Teira and Roxane Therrien and Philippe Ovetchkine and Brigitte Mallette and Henrique von Hertwig Bittencourt},
  journal={Journal of pediatric hematology/oncology},
  year={2014},
  volume={36 5},
  pages={e319-21}
}
Posttransplant lymphoproliferative disease (PTLD) is a life-threatening complication after allogeneic hematopoietic stem cell transplantation. We describe here the case of a boy with history of induction failure of a T-cell acute lymphoblastic leukemia, who presented a life-threatening situation of nonengraftment and rituximab-refractory PTLD after the… CONTINUE READING