Calcification of human vascular cells in vitro is correlated with high levels of matrix Gla protein and low levels of osteopontin expression.

Abstract

The cellular and molecular events leading to calcification in atherosclerotic lesions are unknown. We and others have shown that bone-associated proteins, particularly matrix Gla protein (MGP) and osteopontin (OP), can be detected in atherosclerotic lesions, thus suggesting an active calcification process. In the present study, we aimed to determine whether… (More)

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Cite this paper

@article{Proudfoot1998CalcificationOH, title={Calcification of human vascular cells in vitro is correlated with high levels of matrix Gla protein and low levels of osteopontin expression.}, author={Diane Proudfoot and Jeremy N. Skepper and Camelia Shanahan and P. L. Weissberg}, journal={Arteriosclerosis, thrombosis, and vascular biology}, year={1998}, volume={18 3}, pages={379-88} }