Calbindin in cerebellar Purkinje cells is a critical determinant of the precision of motor coordination.

Abstract

Long-term depression (LTD) of Purkinje cell-parallel fiber synaptic transmission is a critical determinant of normal cerebellar function. Impairment of LTD through, for example, disruption of the metabotropic glutamate receptor-IP3-calcium signaling cascade in mutant mice results in severe deficits of both synaptic transmission and cerebellar motor control… (More)

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Cite this paper

@article{Barski2003CalbindinIC, title={Calbindin in cerebellar Purkinje cells is a critical determinant of the precision of motor coordination.}, author={Jaroslaw Jerzy Barski and Jana Hartmann and Christine R Rose and Freek E. Hoebeek and Karin M{\"o}rl and Michael Noll-Hussong and Chris I De Zeeuw and Arthur Konnerth and Michael Meyer}, journal={The Journal of neuroscience : the official journal of the Society for Neuroscience}, year={2003}, volume={23 8}, pages={3469-77} }