Calbindin and parvalbumin are early markers of non-mitotically regenerating hair cells in the bullfrog vestibular otolith organs

@article{Steyger1997CalbindinAP,
  title={Calbindin and parvalbumin are early markers of non-mitotically regenerating hair cells in the bullfrog vestibular otolith organs},
  author={Peter S Steyger and Matt Burton and Jenny Rae Hawkins and N R Schuff and Richard A. Baird},
  journal={International Journal of Developmental Neuroscience},
  year={1997},
  volume={15},
  pages={417-432}
}
Earlier studies have demonstrated hair cell regeneration in the absence of cell proliferation, and suggested that supporting cells could phenotypically convert into hair cells following hair cell loss. Because calcium-binding proteins are involved in gene up-regulation, cell growth, and cell differentiation, we wished to determine if these proteins were up-regulated in scar formations and regenerating hair cells following gentamicin treatment. Calbindin and parvalbumin immunolabeling was… CONTINUE READING

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