Cajal bodies and histone locus bodies in Drosophila and Xenopus.

  title={Cajal bodies and histone locus bodies in Drosophila and Xenopus.},
  author={Zehra F. Nizami and Svetlana Deryusheva and Joseph G Gall},
  journal={Cold Spring Harbor symposia on quantitative biology},
The organization of the cell nucleus into specialized compartments is important for nuclear function. We address the significance of compartmentalization by studying the Cajal body, an evolutionarily conserved nuclear organelle proposed to be involved in such diverse functions as assembly of the spliceosome, assembly of the transcription machinery, and modification of spliceosomal small nuclear RNAs. The Cajal body is typically identified by the presence of coilin, a protein of poorly defined… CONTINUE READING

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