Caffeine stimulates cytochrome oxidase expression and activity in the striatum in a sexually dimorphic manner.


Epidemiological studies indicate that caffeine consumption reduces the risk of Parkinson's disease (PD) in men, and antagonists of the adenosine 2A receptor ameliorate the motor symptoms of PD. These findings motivated us to identify proteins whose expression is regulated by caffeine in a sexually dimorphic manner. Using mass spectroscopy, we found that… (More)
DOI: 10.1124/mol.108.046888

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