Caffeine reduces myocardial blood flow during exercise.

@article{Higgins2013CaffeineRM,
  title={Caffeine reduces myocardial blood flow during exercise.},
  author={John Patrick Higgins and Kavita M Babu},
  journal={The American journal of medicine},
  year={2013},
  volume={126 8},
  pages={730.e1-8}
}
Caffeine consumption has been receiving increased interest from both the medical and lay press, especially given the increased amounts now available in energy products. Acute ingestion of caffeine usually increases cardiac work; however, caffeine impairs the expected proportional increase in myocardial blood flow to match this increased work of the heart, most notably during exercise. This appears to be mainly due to caffeine's effect on blocking adenosine-induced vasodilatation in the coronary… CONTINUE READING
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