Caffeine potentiates methamphetamine-induced toxicity both in vitro and in vivo.

  title={Caffeine potentiates methamphetamine-induced toxicity both in vitro and in vivo.},
  author={Theerin Sinchai and Surin Plasen and Yupin Sanvarinda and Yamaratee Jaisin and Piyarat Govitrapong and Noppawan Phumala Morales and Piyanee Ratanachamnong and Duangporn Plasen},
  journal={Neuroscience letters},
  volume={502 1},
Ya-Ba, a combination of the two potent psychostimulants methamphetamine (METH) and caffeine (CAF), is commonly used by drug abusers in Thailand and neighboring countries. While the neurotoxic effects of METH are well documented, the toxicity of this combination is mostly unknown. This study aimed to elucidate the effects of this particular drug combination using both in vitro and in vivo models. We found that combined treatment of METH and CAF at individually non-toxic concentrations… CONTINUE READING
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Pharmaco - dynamic interactions between MDMA and concomitants in MDMA tablets on extracellular dopamine and serotonin in the rat brain

  • T. G. Papaioannou Karatzis, K. Aznaouridis, +5 authors M. Mavrikakis
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