Caffeine place conditioning in rats: comparison with cocaine and ethanol.

  title={Caffeine place conditioning in rats: comparison with cocaine and ethanol.},
  author={Nadezhda Patkina and Edwin E. Zvartau},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  volume={8 4},
The present study employed the place conditioning technique to compare rewarding potential of caffeine with that of cocaine and ethanol. In Experiment 1 caffeine, cocaine and ethanol place conditioning were estimated independently, whereas in Experiments 2 and 3 the preference of the external cues associated with caffeine vs. cocaine and caffeine vs. ethanol was assessed in a single test. Caffeine (1.5 mg/kg, i.p.) cocaine (5 mg/kg, i.p.) and ethanol (1.2 g/kg, i.g.) did produce secondary… CONTINUE READING
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