Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.

Abstract

Caffeine, an unspecific antagonist of adenosine receptors, is commonly used to treat the apnea of prematurity. We have defined the effects of caffeine on the carotid body (CB) chemoreceptors, the main peripheral controllers of breathing, and identified the adenosine receptors involved. Caffeine inhibited basal (IC50, 210 microm) and low intensity (PO2… (More)

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Cite this paper

@article{Conde2006CaffeineIO, title={Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.}, author={S{\'i}lvia V Conde and Ana Obeso and Iban Vicario and Ricardo Rigual and Asunci{\'o}n Rocher and C Gonz{\'a}lez}, journal={Journal of neurochemistry}, year={2006}, volume={98 2}, pages={616-28} }