Caffeine ingestion before an oral glucose tolerance test impairs blood glucose management in men with type 2 diabetes.

@article{Robinson2004CaffeineIB,
  title={Caffeine ingestion before an oral glucose tolerance test impairs blood glucose management in men with type 2 diabetes.},
  author={Lindsay E. Robinson and Sonali Savani and Danielle S. Battram and Drew H McLaren and Premila Sathasivam and Terry E. Graham},
  journal={The Journal of nutrition},
  year={2004},
  volume={134 10},
  pages={
          2528-33
        }
}
Caffeine ingestion negatively affects insulin sensitivity during an oral glucose tolerance test (OGTT) in lean and obese men, but this has not been studied in individuals with type 2 diabetes. We examined the effects of caffeine ingestion on insulin and glucose homeostasis in obese men with type 2 diabetes. Men (n = 12) with type 2 diabetes (age = 49 +/- 2 y, BMI = 32 +/- 1 kg/m(2)) underwent 2 trials, 1 wk apart, in a randomized, double-blind design. Each trial was conducted after withdrawal… 
Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training.
TLDR
Caffeine consumption is associated with a substantial reduction in insulin-mediated glucose uptake independent of obesity, type 2 diabetes, and chronic exercise.
Caffeinated coffee consumption impairs blood glucose homeostasis in response to high and low glycemic index meals in healthy men.
TLDR
The ingestion of CC with either a high or low GI meal significantly impairs acute blood glucose management and insulin sensitivity compared with ingestion of DC, and whether CC is a risk factor for insulin resistance is warranted.
Acute caffeine ingestion and glucose tolerance in women with or without gestational diabetes mellitus.
TLDR
Caffeine impaired insulin sensitivity in women with GDM, according to a 2-hour oral glucose tolerance test conducted in a double-blind randomized crossover study.
Glucose homeostasis remains altered by acute caffeine ingestion following 2 weeks of daily caffeine consumption in previously non-caffeine-consuming males
TLDR
Although 14 d of caffeine consumption by previously caffeine-naive subjects reduced its impact on glucose homeostasis, carbohydrate metabolism remained disrupted and caffeine concentrations in serum NEFA and plasma adrenaline concentrations were decreased.
Exaggeration of postprandial hyperglycemia in patients with type 2 diabetes by administration of caffeine in coffee.
TLDR
Repeated on a daily basis, such effects could impair long-term glucose control in those patients with type 2 diabetes who habitually drink coffee or other caffeinated beverages.
Consumption of caffeinated coffee and a high carbohydrate meal affects postprandial metabolism of a subsequent oral glucose tolerance test in young, healthy males
TLDR
Co-ingestion of CC with one meal resulted in insulin insensitivity during the postprandial phase of a second meal in the absence of further CC ingestion, suggesting that CC may play a role in daily glycaemic management.
Caffeine ingestion impairs insulin sensitivity in a dose-dependent manner in both men and women.
TLDR
Results showed that caffeine ingestion disrupted insulin sensitivity in a dose-dependent fashion beginning at very low doses (0-1 mg·kg(-1) BW) in both healthy men and women.
An oral lipid challenge and acute intake of caffeinated coffee additively decrease glucose tolerance in healthy men.
TLDR
Oral consumption of lipids and caffeinated coffee can independently and additively decrease glucose tolerance and could explain at least in part this impaired glucose homeostasis.
Pilot Study of Caffeine Abstinence for Control of Chronic Glucose in Type 2 Diabetes.
TLDR
Although preliminary, these results suggest that caffeine abstinence may be beneficial for patients with type 2 diabetes, and should be confirmed in larger controlled clinical trials.
Caffeine and glucose homeostasis during rest and exercise in diabetes mellitus.
  • D. Zaharieva, M. Riddell
  • Medicine
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
  • 2013
TLDR
Increased coffee intake has been associated with reduced risk of developing type 2 diabetes in large-scale epidemiological studies and the known effects of caffeine on glucose homeostasis and diabetes metabolism during rest and exercise are highlighted.
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