Caffeine-induced diuresis and atrial natriuretic peptides.

@article{Nussberger1990CaffeineinducedDA,
  title={Caffeine-induced diuresis and atrial natriuretic peptides.},
  author={Juerg Nussberger and Pier Angelica Merlini and G. Maridor and Lucienne Juillerat and Bernard Waeber and Hans Rudolf Alfred Brunner},
  journal={Journal of cardiovascular pharmacology},
  year={1990},
  volume={15 5},
  pages={
          685-91
        }
}
After a single-blind, randomized, cross-over protocol using decaffeinated coffee in a control experiment, the effect of an oral 250-mg caffeine dose on plasma immunoreactive atrial natriuretic peptide (ANF) was assessed in eight healthy students who had been on a methylxanthine-free diet for 1 week. One to 2 h after caffeine ingestion, both systolic blood pressure (SBP) and diastolic BP (DBP) increased by 12 mm Hg while heart rate (HR) also tended to increase. An increase in diuresis and in… CONTINUE READING
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