Caffeine decreases exercise-induced myocardial flow reserve.

  title={Caffeine decreases exercise-induced myocardial flow reserve.},
  author={Mehdi Namdar and Pascal Koepfli and Renate Grathwohl and Patrick T. Siegrist and Michael Klainguti and Tiziano Schepis and Raphael Delaloye and Christophe A. Wyss and Samuel P Fleischmann and Oliver Gaemperli and Philipp A. Kaufmann},
  journal={Journal of the American College of Cardiology},
  volume={47 2},
OBJECTIVES We studied the acute effect of caffeine on myocardial blood flow (MBF) at rest and exercise in healthy volunteers at normoxia and during acute exposure to simulated altitude. BACKGROUND Caffeine is a widely consumed stimulant, although its cardiovascular safety remains controversial and its effect on MBF is unknown. METHODS 15O-labeled H2O and positron emission tomography (PET) were used to measure regional MBF at rest and immediately after supine bicycle exercise in healthy… CONTINUE READING


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