Caffeine-death in Escherichia coli

@article{Grigg1968CaffeinedeathIE,
  title={Caffeine-death in Escherichia coli},
  author={Glenn Grigg},
  journal={Molecular and General Genetics MGG},
  year={1968},
  volume={102},
  pages={316-335}
}
Growth of a culture of E. coli strain B or 15 in medium containing caffeine resulted in the accumulation of inviable cells in the population. A caffeine concentration of 8 mM caused the death of between 30% and 50% of the cells in 12 independent populations grown for 15 generations or more. The thymine dimer excision-defective strains Bs-1, Bs-8 and Bs-12 and the exr − mutant Bs-2 were resistant to this lethal effect. The reckless, hcr + mutant Bs-11 was more sensitive than the parental B… CONTINUE READING

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