Caffeine challenge test and panic disorder: a systematic literature review

@article{Vilarim2011CaffeineCT,
  title={Caffeine challenge test and panic disorder: a systematic literature review},
  author={Marina Machado Vilarim and Daniele Marano Rocha Araujo and Ant{\^o}nio Eg{\'i}dio Nardi},
  journal={Expert Review of Neurotherapeutics},
  year={2011},
  volume={11},
  pages={1185 - 1195}
}
This systematic review aimed to examine the results of studies that have investigated the induction of panic attacks and/or the anxiogenic effect of the caffeine challenge test in patients with panic disorder. The literature search was performed in PubMed, Biblioteca Virtual em Saúde and the ISI Web of Knowledge. The words used for the search were caffeine, caffeine challenge test, panic disorder, panic attacks and anxiety disorder. In total, we selected eight randomized, double-blind studies… 
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TLDR
The results suggest that some panic disorder patients may have abnormalities in neuronal systems involving adenosine, and patients with anxiety disorders may benefit by avoiding caffeine-containing foods and beverages.
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TLDR
Preliminary findings indicate that PD patients who panic after a 200 mg or a 400‬mg caffeine challenge, compared to thePD patients who do not panic after both of these challenges, may present at baseline significantly higher non‐specific general psychopathology—as reflected in the SCL‐90‐R—and significantly shorter BH duration.
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TLDR
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TLDR
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