Caffeine can decrease insulin sensitivity in humans.

  title={Caffeine can decrease insulin sensitivity in humans.},
  author={Gerben Keijzers and Bastiaan E. de Galan and Cees J. Tack and Paul Smits},
  journal={Diabetes care},
  volume={25 2},
OBJECTIVE Caffeine is a central stimulant that increases the release of catecholamines. As a component of popular beverages, caffeine is widely used around the world. Its pharmacological effects are predominantly due to adenosine receptor antagonism and include release of catecholamines. We hypothesized that caffeine reduces insulin sensitivity, either due to catecholamines and/or as a result of blocking adenosine-mediated stimulation of peripheral glucose uptake. RESEARCH DESIGN AND METHODS… 

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  • D. ZaharievaM. Riddell
  • Medicine, Biology
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
  • 2013
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