Caffeine can be used for oocyte enucleation.

Abstract

The removal of chromosomes from recipient oocytes is one of the key steps in nuclear transfer cloning. Although microtubule interrupters have been successfully used for oocyte enucleation, their potential side effect on oocyte developmental potential should be considered, and less harmful drugs should be explored for chemical-assisted enucleation. Based on… (More)
DOI: 10.1089/cell.2010.0101

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