Caffeine attenuates liver fibrosis via defective adhesion of hepatic stellate cells in cirrhotic model.

Abstract

BACKGROUND AND AIM Several epidemiological studies have shown that coffee intake attenuates the progression of liver fibrosis; however, the mechanism is unclear. AIMS We investigated the direct effects of caffeine on hepatic stellate cells (HSCs) and assessed whether caffeine attenuated intrahepatic fibrosis in rat model of liver cirrhosis. METHODS… (More)
DOI: 10.1111/jgh.12317

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