Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats.

@article{Shortall2016CaffeineAT,
  title={Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats.},
  author={Sinead E. Shortall and A Richard Green and Kevin C. F. Fone and Madeleine V. King},
  journal={Journal of psychopharmacology},
  year={2016},
  volume={30 7},
  pages={698-706}
}
Administration of caffeine with 3,4-methylenedioxymethamphetamine (MDMA) alters the pharmacological properties of MDMA in rats. The current study examined whether caffeine alters the behavioural and neurochemical effects of mephedrone, which has similar psychoactive effects to MDMA. Rats received either saline, mephedrone (10 mg/kg), caffeine (10 mg/kg) or combined caffeine and mephedrone intraperitoneally twice weekly on consecutive days for three weeks. Locomotor activity (days 1 and 16… CONTINUE READING

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