Caffeine; the Forgotten Potential for Parkinson's Disease.

  title={Caffeine; the Forgotten Potential for Parkinson's Disease.},
  author={Ahmed Negida and Mohamed Elfil and Attia and Eslam Farahat and M. Gabr and A. Essam and D. Attia and H. Ahmed},
  journal={CNS & neurological disorders drug targets},
  volume={16 6},
  • Ahmed Negida, Mohamed Elfil, +5 authors H. Ahmed
  • Published 2017
  • Psychology, Medicine
  • CNS & neurological disorders drug targets
  • BACKGROUND Parkinson's disease (PD) is the second most common neurological disorder characterized by loss of dopaminergic fibers in the basal ganglia and presence of Lewy bodies. METHOD AND RESULTS The literature suggests that caffeine plays multiple roles in PD. Epidemiological studies showed that caffeine intake was associated with less risk of developing PD, especially in genetically susceptible patients. On the level of Lewy bodies' formation, caffeine binds to α-synuclein protein… CONTINUE READING
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