• DOI:10.2174/1871527315666161107091149
Corpus ID: 27990655

Caffeine; the Forgotten Potential for Parkinson's Disease.

@article{Negida2017CaffeineTF,
  title={Caffeine; the Forgotten Potential for Parkinson's Disease.},
  author={Ahmed Negida and Mohamed Elfil and Attia and Eslam Farahat and M. Gabr and A. Essam and D. Attia and H. Ahmed},
  journal={CNS & neurological disorders drug targets},
  year={2017},
  volume={16 6},
  pages={
          652-657
        }
}

Ahmed Negida, Mohamed Elfil, +5 authors H. Ahmed

Published 2017

Psychology, Medicine

CNS & neurological disorders drug targets

BACKGROUND Parkinson's disease (PD) is the second most common neurological disorder characterized by loss of dopaminergic fibers in the basal ganglia and presence of Lewy bodies. METHOD AND RESULTS The literature suggests that caffeine plays multiple roles in PD. Epidemiological studies showed that caffeine intake was associated with less risk of developing PD, especially in genetically susceptible patients. On the level of Lewy bodies' formation, caffeine binds to α-synuclein protein… CONTINUE READING

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