Caffeic and chlorogenic acids inhibit key enzymes linked to type 2 diabetes (in vitro): a comparative study.

  title={Caffeic and chlorogenic acids inhibit key enzymes linked to type 2 diabetes (in vitro): a comparative study.},
  author={Ganiyu Oboh and Odunayo Michael Agunloye and Stephen Adeniyi Adefegha and A J Akinyemi and Adedayo Oluwaseun Ademiluyi},
  journal={Journal of basic and clinical physiology and pharmacology},
  volume={26 2},
BACKGROUND Chlorogenic acid is a major phenolic compound that forms a substantial part of plant foods and is an ester of caffeic acid and quinic acid. However, the effect of the structures of both chlorogenic and caffeic acids on their antioxidant and antidiabetic potentials have not been fully understood. Thus, this study sought to investigate and compare the interaction of caffeic acid and chlorogenic acid with α-amylase and α-glucosidase (key enzymes linked to type 2 diabetes) activities in… CONTINUE READING


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