Caffeic acid phenethyl ester inhibits proliferation and migration, and induces apoptosis in platelet-derived growth factor-BB-stimulated human coronary smooth muscle cells.

@article{Ho2012CaffeicAP,
  title={Caffeic acid phenethyl ester inhibits proliferation and migration, and induces apoptosis in platelet-derived growth factor-BB-stimulated human coronary smooth muscle cells.},
  author={Hung Chin Ho and Ho Ching Chang and Chih Tai Ting and Chan Yen Kuo and Vivian Cheng Yang},
  journal={Journal of vascular research},
  year={2012},
  volume={49 1},
  pages={24-32}
}
BACKGROUND/AIMS Restenosis after a percutaneous coronary intervention (PCI) during treatment for coronary artery disease is closely related to smooth muscle cell (SMC) proliferation and migration. In this study, we investigated the effects of caffeic acid phenethyl ester (CAPE) and its underlying mechanism on human coronary SMCs (HCSMCs) after platelet-derived growth factor-BB (PDGF-BB) stimulation in vitro. METHODS AND RESULTS The results showed that CAPE inhibited proliferation and… CONTINUE READING

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