Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers.

@article{Scapagnini2002CaffeicAP,
  title={Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers.},
  author={G. Scapagnini and R. Foresti and V. Calabrese and A. G. Giuffrida Stella and C. Green and R. Motterlini},
  journal={Molecular pharmacology},
  year={2002},
  volume={61 3},
  pages={
          554-61
        }
}
Heme oxygenase-1 (HO-1) is a redox-sensitive inducible protein that provides efficient cytoprotection against oxidative stress. Curcumin, a polyphenolic natural compound that possesses anti-tumor and anti-inflammatory properties, has been reported recently to induce potently HO-1 expression in vascular endothelial cells (Free Rad Biol Med 28:1303-1312, 2000). Here, we extend our previous findings by showing that caffeic acid phenethyl ester (CAPE), another plant-derived phenolic agent, markedly… Expand
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  • Shuang Liu, W. Hou, +5 authors Liegang Liu
  • Chemistry, Medicine
  • Toxicology in vitro : an international journal published in association with BIBRA
  • 2012
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