Caffeic acid phenethyl ester ameliorated ototoxicity induced by cisplatin in rats.

  title={Caffeic acid phenethyl ester ameliorated ototoxicity induced by cisplatin in rats.},
  author={Ahmet Kizilay and Mahmut Tayyar Kalcioglu and Elif Ozerol and Mustafa Iraz and Mukaddes Gulec and Omer Akyol and Orhan Ozturan},
  journal={Journal of chemotherapy},
  volume={16 4},
Caffeic acid phenethyl ester (CAPE), an active component of propolis, exhibits antioxidant properties. This experimental study was designed to determine the effect of CAPE on ototoxicity induced with cisplatin. Twenty-four adult Wistar albino rats were divided into four groups: cisplatin (n=6), saline (n=6), CAPE (n=6), and cisplatin plus CAPE (n=6). Rats were tested before and 5 days after cisplatin treatment with or without chemo protection. The Distortion Product Otoacoustic Emissions… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 16 extracted citations

The protective role of caffeic acid phenethyl ester against streptomycin ototoxicity.

American journal of otolaryngology • 2013
View 3 Excerpts
Highly Influenced

The Effect of Dexpanthenol on Ototoxicity Induced by Cisplatin

Clinical and experimental otorhinolaryngology • 2016
View 1 Excerpt

Similar Papers

Loading similar papers…