Caffeic acid phenethyl ester ameliorated ototoxicity induced by cisplatin in rats.

@article{Kizilay2004CaffeicAP,
  title={Caffeic acid phenethyl ester ameliorated ototoxicity induced by cisplatin in rats.},
  author={Ahmet Kizilay and Mahmut Tayyar Kalcioglu and Elif Ozerol and Mustafa Iraz and Mukaddes Gulec and Omer Akyol and Orhan Ozturan},
  journal={Journal of chemotherapy},
  year={2004},
  volume={16 4},
  pages={381-7}
}
Caffeic acid phenethyl ester (CAPE), an active component of propolis, exhibits antioxidant properties. This experimental study was designed to determine the effect of CAPE on ototoxicity induced with cisplatin. Twenty-four adult Wistar albino rats were divided into four groups: cisplatin (n=6), saline (n=6), CAPE (n=6), and cisplatin plus CAPE (n=6). Rats were tested before and 5 days after cisplatin treatment with or without chemo protection. The Distortion Product Otoacoustic Emissions… CONTINUE READING

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