Caffeic acid derivatives isolated from the aerial parts of Galinsoga parviflora and their effect on inhibiting oxidative burst in human neutrophils

  title={Caffeic acid derivatives isolated from the aerial parts of Galinsoga parviflora and their effect on inhibiting oxidative burst in human neutrophils},
  author={Marta K. Dudek and Łukasz Dudkowski and Agnieszka Bazylko and Sławomir Kaźmierski and Anna K. Kiss},
  journal={Phytochemistry Letters},
Ethnobotanical, phytochemical and pharmacological properties of Galinsoga parviflora (Asteraceae): A review
Crude extracts and pure compounds isolated from the plant possess potent pharmacological activities such as antibacterial, antifungal, antioxidant, anti-inflammatory and nematicidal effects.
Both species showed a tendency to promote cytotoxicity in human lymphocyte cells and antiproliferative potential in the assay with AGS cells, which reinforce the medicinal use of these plants, as well as suggest their potential use for the development of new drugs and for the treatment of cancers.
Caffeic acid derivatives isolated from Galinsoga parviflora herb protected human dermal fibroblasts from UVA-radiation.
  • A. Parzonko, A. Kiss
  • Biology
    Phytomedicine : international journal of phytotherapy and phytopharmacology
  • 2019
Feature-Based Molecular Networking to Target the Isolation of New Caffeic Acid Esters from Yacon (Smallanthus sonchifolius, Asteraceae)
The outcome of the current study confirms the utility of feature-based molecular networking as a tool for targeted isolation of previously undescribed metabolites and reveals the full diversity of potentially bioactive metabolites from S. sonchifolius.
Calendula arvensis (Vaill.) L.: A Systematic Plant Analysis of the Polar Extracts from Its Organs by UHPLC-HRMS
Calendula arvensis (Vaill.) L. (field marigold, Asteraceae) is an alimurgic plant, whose flowers and leaves are a common part of local food dishes. The diversity in polar specialized metabolites is
Ethnobotanical and pharmacological profile of galinsoga parviflora
This study focuses on Galinsoga parviflora's ethno-medicinal usage, isolated natural components, and biological activity, and properties have been observed in crude extracts and pure chemicals obtained.
High efficacy of (Z)-γ-bisabolene from the essential oil of Galinsoga parviflora (Asteraceae) as larvicide and oviposition deterrent against six mosquito vectors
The oviposition deterrent potential of the G. parviflora EO and (Z)-γ-bisabolene was studied on six mosquito vectors, showing that 25 μg/ml of (Z), led to an Oviposition Activity Index lower of − 0.79 in all tested mosquito vectors.


Caffeic acid derivatives in the roots of yacon (Smallanthus sonchifolius).
Five caffeic acid derivatives were found in the roots of yacon, Smallanthus sonchifolius, as the major water-soluble phenolic compounds in plants of the family Asteraceae.
Caffeic Acid Derivatives from Eupatorium perfoliatum L.
From the ethyl acetate soluble fraction of a methanol/water extract of the herb Eupatorium perfoliatum L. (Asteraceae) six caffeic acid derivatives have been isolated and identified by 1D- and 2D-NMR
Isolation and structural elucidation of anthocyanidin 3,7-β-O-diglucosides and caffeoyl-glucaric acids from calafate berries.
The anthocyanidin dihexosides constitute the complete series of 3,7-β-O-diglucosides of the five anthocianidins usually found in calafate, the structures of which were completely elucidated in the cases of delphinidin, petunid in, and malvidin derivatives and tentatively suggested in the case of cyanidin and peonidin.
Determination of antioxidant activity of extracts and fractions obtained from Galinsoga parviflora and Galinsoga quadriradiata, and a qualitative study of the most active fractions using TLC and HPLC methods
The research demonstrates that the investigated herbs are an interesting source of preparations with significant antioxidant effects and justifies the use of both raw materials in inflammatory diseases, among others, due to their ability to prevent free radical-induced deleterious effects.
Galinsosides A and B, bioactive flavanone glucosides from Galinsoga parviflora
New flavanone glucosides A and B have been isolated from an ethyl acetate- soluble fraction of Galinsoga parviflora and showed significant antioxidant and urease inhibitory activity while compound 2 was moderately active.
In vitro 5-Lipoxygenase inhibition of polyphenolic antioxidants from undomesticated plants of South Africa
Large amounts of phenolic compounds may contribute towards the antioxidant and anti-inflammatory properties among the plants studied and a correlation between radical scavenging activity of extracts with total phenolic content was observed.
Metabolomic analysis reveals that the accumulation of specific secondary metabolites in Echinacea angustifolia cells cultured in vitro can be controlled by light
The results are significant because they suggest that the metabolic profile of cell cultures can be manipulated by controlling simple environmental variables such as illumination to modulate the levels of potentially therapeutic compounds.