Caffeic acid, a phyto polyphenol mitigates fluoride induced hepatotoxicity in rats: A possible mechanism.

@article{Kanagaraj2015CaffeicAA,
  title={Caffeic acid, a phyto polyphenol mitigates fluoride induced hepatotoxicity in rats: A possible mechanism.},
  author={Vishnu Vignesh Kanagaraj and Lakshmikanthan Panneerselvam and Vimal Govindarajan and Jaishabanu Ameeramja and E. Perumal},
  journal={BioFactors},
  year={2015},
  volume={41 2},
  pages={
          90-100
        }
}
  • Vishnu Vignesh Kanagaraj, Lakshmikanthan Panneerselvam, +2 authors E. Perumal
  • Published 2015
  • Medicine, Chemistry
  • BioFactors
  • Fluoride induced hepatotoxicity has been extensively studied in both humans and animals. However, the mechanism underlying in the hepatotoxicity of experimental fluorosis remains obscure. The severity of fluoride toxicity was reduced by oral administration of certain plant derived antioxidants. Caffeic acid (CA) a polyphenolic compound has diverse range of pharmacological activity in the biological system. Therefore, the present study was aimed to investigate the protective mechanism of CA… CONTINUE READING
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