Caesalpinia sappan: A promising natural source of antimicrobial agent for inhibition of cariogenic bacteria.

@article{Puttipan2018CaesalpiniaSA,
  title={Caesalpinia sappan: A promising natural source of antimicrobial agent for inhibition of cariogenic bacteria.},
  author={Rinrampai Puttipan and Sunee Chansakaow and Sakornrat Khongkhunthian and Siriporn Okonogi},
  journal={Drug discoveries \& therapeutics},
  year={2018},
  volume={12 4},
  pages={
          197-205
        }
}
From the previous findings, the ethanolic fractionated extract of Caesalpinia sappan (F-EtOH) has high activity against Streptococcus mutans, the most severe cariogenic bacteria. The present study was aimed to isolate and identify the active compound of F-EtOH and compare its inhibitory activity against the biofilm of S. mutans as well as the cytotoxicity to oral fibroblast cells with F-EtOH. Compound isolation was done by column chromatography. The active compound was identified using liquid… Expand
Effect of Ethanolic Caesalpinia sappan Fraction on In Vitro Antiviral Activity against Porcine Reproductive and Respiratory Syndrome Virus
TLDR
In vitro antiviral activity against PRRSV of a semi-purified fraction of ethanolic CS crude extract using preparative high-performance liquid chromatography is focused on and useful information is provided for further study to effectively develop the CS bioactive antiviral compounds againstPRRSV as a feed additive or veterinary drug in the pig industry. Expand
Natural dye from Caesalpinia sappan L. heartwood for eco-friendly coloring of recycled paper based packing material and its in silico toxicity analysis
TLDR
The extracted dye had a good photostability and able to make imprints on recycled paper bags and a significant inhibition of bacterial growth was observed at a higher dye concentration of 100 μg mL−1 against P. aeruginosa which was higher than the standard antibiotics. Expand

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