Corpus ID: 36423861

Caerulein-induced desensitization of enzyme secretion fails in neonatal rat pancreas.

@article{Papp1989CaeruleininducedDO,
  title={Caerulein-induced desensitization of enzyme secretion fails in neonatal rat pancreas.},
  author={M. Papp and G. Varga and I. Dobronyi},
  journal={Acta physiologica Hungarica},
  year={1989},
  volume={74 3-4},
  pages={
          305-10
        }
}
Pancreatic segments of 1-, 3-, 5-, 10-day-old and adult female OFA (Sprague-Dowley strain) rats were superfused with graded concentrations of caerulein (10(-12)-10(-7) M) to establish concentration-response relation of amylase release. Furthermore, pancreatic segments of 3-, 5-, 10-day-old and adult rats were superfused with 10(-10) or 10(-8) M caerulein and then superfusion was repeated with 10(-10) M concentration of caerulein to show whether the phenomenon of desensitization of amylase… Expand