Caerulein and its analogues: Neuropharmacological properties

@article{Zetler1985CaeruleinAI,
  title={Caerulein and its analogues: Neuropharmacological properties},
  author={Gerhard Zetler},
  journal={Peptides},
  year={1985},
  volume={6},
  pages={33-46}
}
The decapeptide from the frog Hyla caerulea, caerulein (caerulein diethylammonium hydrate, ceruletide, CER) is chemically closely related to the C-terminal octapeptide of cholecystokinin (CCK-8). Like CCK-8, CER and some of its analogues produce many behavioural effects in mammals: inhibition of intake of food and water; antinociception; sedation; catalepsy; ptosis, antistereotypic, anticonvulsive and tremorolytic effects; inhibition of self-stimulation. Effects of CER in man comprise sedation… CONTINUE READING
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