Caenorhabditis elegans glutamate transporters influence synaptic function and behavior at sites distant from the synapse.

@article{Mano2007CaenorhabditisEG,
  title={Caenorhabditis elegans glutamate transporters influence synaptic function and behavior at sites distant from the synapse.},
  author={Itzhak Mano and Sarah Straud and Monica Driscoll},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 47},
  pages={34412-9}
}
To ensure precise neurotransmission and prevent neurotoxic accumulation, l-glutamate (Glu), the major excitatory neurotransmitter in the brain, is cleared from the synapse by glutamate transporters (GluTs). The molecular components of Glu synapses are highly conserved between Caenorhabditis elegans and mammals, yet the absence of synaptic insulation in C. elegans raises fundamental questions about Glu clearance strategies in the nematode nervous system. To gain insight into how Glu clearance is… CONTINUE READING
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References

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Transduction Channels in Sensory Cells

L. Bianchi, M. Driscoll
2004

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